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Hormones / EndocrineTier 2 · Mid-Specialty

ANTI MULLERIAN HORMONE (AMH)

Also known as: AMH · Müllerian Inhibiting Substance · MIS · AMH Test · Ovarian Reserve Test

Sample: Serum Reference price: ₹1986Code: ZNT-ANTIMULLERIANHORMONEAMH

What this test measures

Anti-Müllerian Hormone (AMH) is produced by the granulosa cells of small antral follicles in the ovary. The level is proportional to the size of the resting follicle pool — in other words, how many eggs you have in reserve. Unlike FSH, AMH stays relatively stable across the menstrual cycle and can be tested on any day.

In men, AMH is produced by the Sertoli cells of the testis. The clinical use in adult men is limited, but in boys with undescended testis or ambiguous genitalia, AMH is a key marker of functional testicular tissue.

Why it matters

AMH is the single best biochemical predictor of ovarian response to IVF stimulation — every Indian fertility clinic uses it in their initial workup. Beyond IVF, it helps frame realistic conversations with women planning to delay pregnancy, guides oocyte-freezing decisions, and gives a rough idea of how close someone may be to menopause.

AMH is also reproducibly raised in PCOS (often > 4 ng/mL), reflecting the increased antral follicle count seen on ultrasound. In oncology, an AMH after chemotherapy quantifies how much ovarian reserve has been lost.

AMH does not predict whether you will conceive — many women with low AMH conceive spontaneously, and a high AMH does not protect against infertility from tubal or uterine causes.

How to prepare

No fasting and no cycle-day requirement — AMH can be drawn on any day. Stop biotin / cosmetic supplements for 48–72 hours before. If you are on combined oral contraceptive pills, expect a 20–30% lower reading; ideally test 3 months after stopping if you want the most accurate baseline. Continue other medications.

Markers & reference ranges

Reference ranges below are typical adult values. Your lab's reported range may differ slightly based on the assay platform and patient demographics — always read your report against the range printed on it.

MarkerNormal rangeIf lowIf high
Anti-Müllerian Hormone (AMH) (ng/mL)[1][2]< 25 yr: 1.5 – 4.0 · 25–34 yr: 1.0 – 3.5 · 35–40 yr: 0.7 – 2.5 · > 40 yr: 0.3 – 1.5 · Postmenopausal: < 0.1< 1.0 ng/mL = low ovarian reserve. < 0.5 ng/mL = severely diminished — fertility window is narrow, IVF cycles require aggressive stimulation and outcomes are less predictable. < 0.1 ng/mL is consistent with menopause.> 4.0 ng/mL in a young adult is suggestive of PCOS — high antral follicle count and risk of an exaggerated response (and OHSS) on IVF stimulation. Granulosa cell tumours can produce very high AMH but are rare.

AMH — how to read your number

AMH (ng/mL)InterpretationTypical implication
> 4.0HighPossible PCOS; high IVF response; OHSS risk
1.0 – 4.0Normal-for-ageReassuring ovarian reserve
0.5 – 1.0LowDiminished reserve — consider not delaying pregnancy further
< 0.5Severely diminishedIVF possible but lower egg yield; consider donor options if attempts fail
< 0.1Menopausal rangeConsistent with menopause / premature ovarian insufficiency

Frequently asked questions

Does my AMH tell me if I can get pregnant?

No. AMH predicts how many eggs you have in reserve and how the ovary is likely to respond to IVF stimulation. It does not tell you whether an egg will fertilise, implant or carry to term — that depends on egg quality, sperm, tubes, uterus and overall health.

I am 32 and my AMH is 0.6 — should I worry?

It does mean ovarian reserve is lower than typical for your age, which usually counsels against delaying pregnancy further. But many women with AMH in this range conceive naturally. A reproductive endocrinologist can help plan timing or fertility preservation.

Does AMH change over the menstrual cycle?

Very little — much less than FSH or estradiol. You can draw the sample on any day, which is one of the practical advantages of AMH.

My birth control pill is in the way — should I stop it?

Hormonal contraception lowers AMH by 20–30%. If your AMH on the pill is reassuring (>1 ng/mL), it is essentially reliable. If it is borderline, your doctor may repeat 3 months after stopping the pill.

I am being told my AMH is "high" — is that good?

High AMH in a young woman often indicates PCOS — the ovary has many small follicles but does not always ovulate them. It is not "more fertility" — many women with high AMH still struggle to conceive because of irregular ovulation.

Can AMH predict menopause?

In broad terms, yes — a very low AMH suggests menopause is closer. But the prediction is much better in years than in months: a single AMH cannot tell you the exact age you will reach menopause.

Does AMH change after pregnancy or breastfeeding?

AMH falls during pregnancy and stays slightly suppressed during breastfeeding, returning to baseline a few months after weaning. If a low postpartum AMH is concerning, repeat in 3–6 months.

Can lifestyle improve my AMH?

No reliable lifestyle intervention raises AMH. Stopping smoking, achieving a healthy BMI and managing thyroid disease support overall fertility, but the ovarian reserve itself is largely fixed.

Related Hormones / Endocrine tests

Tests commonly ordered alongside ANTI MULLERIAN HORMONE (AMH), or that help interpret an unexpected result.

Sources & references

  1. ASRM — Testing and Interpreting Measures of Ovarian Reserve · accessed 2026-05-30T00:00:00.000Z
  2. NIH MedlinePlus — AMH Test · accessed 2026-05-30T00:00:00.000Z
  3. NCBI StatPearls — Anti-Mullerian Hormone · accessed 2026-05-30T00:00:00.000Z
  4. ESHRE — Ovarian Stimulation for IVF Guideline · accessed 2026-05-30T00:00:00.000Z

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